- New York Mets traded Jack Hamilton to the California Angels for Nick Willhite on June 10, 1967.
- New York Mets traded Hawk Taylor to the California Angels for Don Wallace on July 24, 1967.
- New York Mets traded Nolan Ryan, Leroy Stanton, Frank Estrada and Don Rose to the California Angels for Jim Fregosi on December 10, 1971.
- New York Mets traded Ike Hampton to the California Angels for Ken Sanders on March 22, 1975.
- New York Mets purchased Gil Flores from the California Angels on July 28, 1978.
- California Angels signed Ellis Valentine of the New York Mets as a free agent on January 21, 1983.
- New York Mets traded Shane Young and Jeff Richardson to the California Angels for John Candelaria on September 15, 1987.
- New York Mets traded Hubie Brooks to the California Angels for Dave Gallagher on December 10, 1991.
- New York Mets traded Julio Valera and Julian Vasquez to the California Angels for Dick Schofield on April 12, 1992.
- New York Mets traded Aaron Ledesma to the California Angels for Kevin Flora on January 18, 1996.
- New York Mets signed free agent Allen Watson of the Anaheim Angels on January 19, 1999.
- Anaheim Angels signed David Lamb of the New York Mets as a free agent on November 8, 2000.
- New York Mets traded Kevin Appier to the Anaheim Angels for Mo Vaughn on December 27, 2001.
- Anaheim Angels signed Jason Middlebrook of the New York Mets as a free agent on February 9, 2004.
- Los Angeles Angels signed Darren Oliver of the New York Mets as a free agent on December 11, 2006.
- New York Mets signed free agent Francisco Rodriguez of the Los Angeles Angels on December 10, 2008.
- New York Mets selected Darren O'Day in free agent draft on December 11, 2008.
- New York Mets traded Brian Stokes to the Los Angeles Angels for Gary Matthews on January 22, 2010.
- Los Angeles Angels signed Hisanori Takahashi of the New York Mets as a free agent on December 2, 2010.
- Los Angeles Angels signed Jason Isringhausen of the New York Mets as a free agent on February 22, 2012.
- New York Mets signed free agent LaTroy Hawkins of the Los Angeles Angels on January 31, 2013.
- New York Mets sold Elvin Ramirez to the Los Angeles Angels on March 27, 2013.
- New York Mets traded Collin Cowgill to the Los Angeles Angels for Kyle Johnson on June 25, 2013.
- Los Angeles Angels claimed Robert Carson of the New York Mets on waivers on October 17, 2013.
- New York Mets sold Kirk Nieuwenhuis to the Los Angeles Angels on May 27, 2015.
- New York Mets claimed Kirk Nieuwenhuis on waivers from the Los Angeles Angels on June 13, 2015.
- New York Mets traded Erik Manoah to the Los Angeles Angels for Fernando Salas on August 31, 2016.
- Los Angeles Angels claimed Hansel Robles of the New York Mets on waivers on June 23, 2018.
- Los Angeles Angels claimed Jacob Rhame of the New York Mets on waivers on July 8, 2020.
- Los Angeles Angels signed Noah Syndergaard of the New York Mets as a free agent on November 16, 2021.
- Los Angeles Angels signed Aaron Loup of the New York Mets as a free agent on November 22, 2021.
- Los Angeles Angels claimed Rob Zastryzny of the New York Mets on waivers on August 25, 2022.
- New York Mets traded Eduardo Escobar to the Los Angeles Angels for Landon Marceaux and Coleman Crow on June 24, 2023.
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